Viphoria is the brain child of pharmaceutical scientist Dr. Keletso Mabalane, a prodigy and the pride of medical scientific development in South Africa. With the financial assistance of a major pharmaceutical company, Keletso launches an intensive drug trial for Viphoria for the eventual distribution and sale to the general public once approved by the relevant medical regulatory bodies. The trial runs for three months at a wellness centre where each participant is given a daily dose of the drug and they are extensively monitored and studied by Keletso and her medical support team. After a seemingly successful run with a group of male participants, the film opens with the beginning of the female trial. A start which is threatened by the national news that one of the trial’s male participant’s committed suicide even after being “cured” by Keletso. Desperate to distract from this indictment against her drug, Keletso invites Liana Mthimkhulu to join the women’s trial.